Summary

We are seeking a highly motivated postdoctoral researcher to join our team of drug development. The goal of our projects is to develop onco-immunology small molecules for cancer immunotherapy and immune modulators for treatment of autoimmune diseases.

This position is within a multi-disciplinary and highly collaborative research group. The successful applicant should have a strong background in organic/medicinal chemistry, and also show interest in other areas of research relevant to the lab such as cancer nanomedicine, cancer mRNA vaccine and pharmacokinetics. Our lab research interest is listed at https://pharmacy.umich.edu/sun-lab.

Responsibilities*

• Create hypotheses, design compounds, and carry out multi-step synthesis of small molecules.
• Analyze complex data sets to generate hypotheses for structure and properties optimization.
• Regular report of research progress in group meeting and active participation in discussion.
• Work well independently and as a member of a highly collaborative team.

Required Qualifications*

• PhD (or equivalent degree) in Organic/ Medicinal Chemistry.
• Strong ability to implement synthetic/medicinal chemistry design strategies to address compound liabilities.
• Solid mechanistic understanding to perform troubleshooting.
• Good knowledge of common purification and analytical methods such as HPLC, Column chromatography, LC-MS, or NMR.

Desired Qualifications*

• Experience in molecular modeling or ligand/protein structure visualization to propose hypotheses for optimization.
• Excellent communication skills.
• Well organized and ability to multi-task.

Background Screening

The University of Michigan conducts background checks on all job candidates upon acceptance of a contingent offer and may use a third party administrator to conduct background checks. Background checks are performed in compliance with the Fair Credit Reporting Act.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.