School of Medicine:
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Post-doctoral position available immediately for research on genome editing in rare genetic diseases. Genome editing with adeno-associated virus vectors is a major focus of the laboratory. The project will include invivo genome editing to treat glycogen storage disea se (GSD), either GSD typeIa or Pompe disease. A second focus is to develop small molecules to stimulate autophagy and reverse the abnormalities of autophagy in GSD. New drug therapy for GSD will have implications for the treatment of more common conditions, including non-alcoholic fatty liver disease and diabetic nephropathy. Representative publications describe the scope of this project.1-6 Duke University features outstanding clinical and scientific resources with opportunities for local and international collaboration. This position will support an active collaboration with established genome editing, autophagy, and virology research groups. Candidates with molecular biology experience, and familiarity with viral vectors, immunology, and/or biochemistry are encouraged to apply. Ph.D. and/or M.D. required. The position is located in Dwight Koeberl’s laboratory in the Department of Pediatrics and Division of Medical Genetics, and the Molecular Genetics and Microbiology Department at Duke University.
Website: https:// scholars.duke.edu/display/per3329362
Interested candidates should submit their electronic application to firstname.lastname@example.org that should include: (1) the names of 3 references, and (2) an updated CV.
Education - PhD or MD required.
Experience with molecular biology experience, and familiarity with viral vectors, immunology, and/or biochemistry preferred.
Job Code: 00003820 POSTDOCTORAL ASSOCIATE
Job Level: 00
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