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PostDoctoral Associate in Biophysics and Structural Biology
Rutgers University in New Brunswick, New Jersey
Date Posted 01/18/2021
Admin-Other Administrative Positions
Employment Type
Application Deadline Open until filled

Position Details

Recruitment/Posting Title PostDoctoral Associate in Biophysics and Structural Biology
Department Proteomics
Salary Commensurate With Experience
Posting Summary

A postdoctoral position in cryo-electron microscopy (cryo-EM) and single-molecule studies of DNA repair and replication is available in the laboratory of Dr. Arek Kulczyk in the Institute for Quantitative Biomedicine at Rutgers University.

Kulczyk lab ( integrates structural approaches, in particular single-particle cryo-EM, single-molecule methods and novel correlative light and electron microscopy (CLEM) techniques to study DNA replication and repair (Kulczyk et al., 2017, PNAS, 114:1848; Duderstadt et. al., 2016, Mol Cell, 64:1035; Geertsema et al., 2014, PNAS, 111:4073; Kulczyk et al., 2012, PNAS, 109:9408; Loparo et al., 2011, PNAS, 108:3584).

Posting Number 21FA0035
Posting Open Date 01/14/2021
Posting Close Date

Minimum Education and Experience

Applicants must hold a PhD in biophysics or in a related field and have a deep working knowledge of structural biology.

Required Knowledge, Skills, and Abilities

Proficiency in cloning, protein expression, protein purification, and characterization of protein-nucleic acid complexes using a variety of biophysical methods (for example: BIAcore, ITC, AUC, DLS and NMR). Research experience in cryo-electron microscopy (cryo-EM) and single-molecule biophysics is desirable, however not required. The selected candidate will obtain appropriate training in microscope alignments, data acquisition, image processing and structure calculation using a variety of cryo-EM software. The candidate should be proficient in Linux. Working knowledge of C++, Python, CUDA and experience in high performance computing (HPC) is desirable, but not required. Strong written and oral communication skills in English, as well as the ability to work independently and prepare scientific manuscripts are required.

Equipment Utilized

The Institute for Quantitative Biomedicine houses the state-of-the-art cryo-EM facility (Thermo Fisher Scientific Talos Arctica cryo-electron microscope equipped with a Summit K2 direct electron detector, BioQuantum energy filter and a Volta phase plate; Leica DM6 FS/EM cryo-CLEM system), NMR facility (Bruker 800 MHz and 700 MHz with cryoprobes and two 600 MHz spectrometers), mass spectrometry and super-resolution imaging facilities, and is the world headquarters of the Research Collaboratory for Structural Bioinformatics (RCSB) consortium and the Protein Data Bank (PDB). In addition, the effort to purchase Thermo Fisher Scientific Titan Krios and dual-beam FIB-SEM instruments is under way.

Physical Demands and Work Environment

Special Instructions to Applicants
Quick Link to Posting
Campus Rutgers University-New Brunswick
Home Location Campus Busch (RU-New Brunswick)
Location Details

*Please mention to employers when applying for this job*
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260 Peachtree Street, N.W.
Suite 2200
Atlanta, GA 30303
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