Contributes to our efforts in developing a high-throughput, integrated plate system containing human pluripotent stem cell (PSC)-derived liver, pancreas, and intestine tissues to simulate normal/diseased mechanisms involved in inter-organ communication and investigating how hormones, nutrients, and drugs might mediate the reversal of type II diabetes. Works toward establishing PSC-derived human tissue culture (i.e., organoids) on unique pillar/perfusion plate platforms and perform a suite of high-content imaging assays to detect critical changes in organoid/tissue morphology in 3D, cell functions, molecular actions on cell surface receptors, and mechanisms of drug action. Interacts professionally with all internal and external collaborators and graduate students/senior scientists using strong interpersonal skills.
Must hold a PhD degree in biomedical engineering, biotechnology, molecular biology, or related areas. Must have a strong background and hands-on experience in one or more of these areas: stem cell biology, 3D cell culture, organoid culture, immunofluorescence staining, high-content imaging assays, and molecular biology techniques including recombinant lentivirus construction and amplification. Must be highly motivated in interdisciplinary research. Will participate in NIH-funded research projects.
Previous experience in stem cell and organoid culture, immunofluorescence staining, and molecular biology techniques.
Date grant, position, or appointment expires (For Funds Available, Temporary, and Waiver of Posting
Special Instructions to Applicants
Please include a cover letter and CV (with publication record) with your submitted application. This vacancy will have the possibility of renewal pending grant approval.
Offer of employment is contingent on satisfactory completion of the University’s verification of credentials and other information required by law and/or University policies or practices, including but not limited to a criminal background check. Mailed or emailed application materials will not be accepted.
Full Time/Part Time
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