SUBFUNCTION DEFINITION: The healthcare science that determines the safety and effectiveness (efficacy) of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatment, diagnosis or for relieving symptoms of a disease. To ensure quality, human subject safety and data integrity of clinical trials conducted within the assigned department.
Cincinnati Children's Research Foundation; CCHMC Affiliates
TOTAL NUMBER OF FTE's DIRECTLY OR INDIRECTLY SUPERVISED:
PURPOSE OF POSITION:
A postdoctoral Research Fellow position is available immediately in Dr. Douglas Millay’s lab in the Division of Molecular Cardiovascular Biology at Cincinnati Children’s Hospital Research Foundation. The Millay lab is interested in understanding the formation of multi-nucleated skeletal muscle, which arises from the membrane fusion between precursor cells (myoblast fusion). Projects include delineating the mechanisms by which novel muscle membrane proteins directs cell-cell fusion, understanding the role of fusion and myonuclear accretion for muscle physiology, and harnessing the muscle cell fusion machinery as a strategy for in vivo delivery of therapeutic material. For more information see:
About Cincinnati Children's
Cincinnati Children’s Hospital Medical Center is a premier pediatric research institution with over 900 diverse and productive faculty members. Here, researchers work collaboratively across specialties and divisions to address some of the biggest challenges we face today in improving child health. A strong network of research support services and facilities, along with institutional commitment to research, push our team of faculty, postdocs and support staff to explore the boundaries of what is possible, leading to significant breakthroughs. We are driven by our mission to improve child health and transform the delivery of care through fully integrated, globally recognized research, education and innovation.
Post-doctoral research fellows at Cincinnati Children’s are valued for their unique interests and strengths, and are supported by our institution’s strong programming for post-docs through the Office of Postdoctoral Affairs and the Office of Academic Affairs and Career Development. Mentoring, support for international students and an emphasis on crafting high-quality grant proposals are only a few of the features that set our program apart. Cincinnati Children’s is a respected part of the broader, and very vibrant, Cincinnati community. With a thriving arts scene, numerous festivals celebrating music and food, a passionate fan following for our college and professional sports teams, and a variety of opportunities for outdoor activities, our region is truly a great place to work and live.
Design, execute and record laboratory experiments; apply standard scientific/research protocols to experiments, research and improve current methods and evaluate innovative techniques. Design and perform experiments and record data according to research protocol. Independently reproduce, evaluate, research and improve techniques currently used. Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition. Maintain accurate and detailed records of all laboratory work and experiments. Develop, set-up and verify new procedures in the laboratory. Standardize and establish new published procedures; evaluate innovative techniques. Develop new assays and new protocols; design formats. Discuss relevant insights about experimental results with Director and provide useful recommendations and analysis. Troubleshoot and correct erroneous results or problems with laboratory equipment. Maintain and repair equipment; monitor proper use by personnel. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks. Demonstrate performance at work, consistency in carrying out instructions, accuracy & attention to detail, achieving expected results & continuous improvement.
Draft, write and edit scientific reports, papers, journal articles and abstracts. Present at local, national and international scientific meetings.
Train and supervise the work of other laboratory personnel as appropriate. Maintain an integral role in the laboratory's meetings, presentations and publications. Present information on research and laboratory work to others at laboratory meetings, journal clubs and seminars. Demonstrate attendance and punctuality, ability to work independently & display initiative and dedication
Assist in preparing, writing and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve and initiate check requests; track funding, maintain accurate balance and resolve any discrepancies.
May act as a mentor to more junior staff, serve as the contact for resolution of complex issues, provide education, guidance and work direction. May provide input and feedback to managers on hiring decisions, professional development and performance management.
- PhD in a related field, MD or equivalent degree AND
- 3 years related postdoctoral research experience.
PREFERRED:Recent Ph.D candidates with research experience in molecular biology, cell biology, biochemistry, or developmental biology are encouraged to apply.
Ability to perform clerical functions with accuracy and attention to detail
Considering multiple perspectives or challenging traditional assumptions; formulating unusual, clever ideas or developing new insights; astutely identifying new ideas that will improve organizational functions, products, or services
Locating and gathering relevant information; recognizing and working to eliminate important gaps in existing information; determining the value of the information; synthesizing and organizing information to get a better understanding of a problem
Willingness to serve as an education resource to others
Ability to supervise others
Proficiency in basic computer applications such as Microsoft Office (PowerPoint, Word, Excel), e-mail, and internet
Meticulously keeping track of details without becoming overwhelmed by them; being exacting, precise, and accurate; spotting minor imperfections or errors and taking action to correct them
Strong organizational and project management skills to handle projects independently.
Prioritization and time-management skills sufficient to meet deadlines in a fast-paced environment
Analytical ability sufficient to evaluate data, make judgments and recommendations
- Statistics - Intermediate
Familiarity with statistical software, statistical techniques, statistical process control principles, and graphical data display
- Lab Procedures - Advanced
Knowledge and the ability necessary to independently perform advanced laboratory procedures
Ability to express results in the form of oral/written presentations suitable for publication and/or funding
Excellent verbal, written and interpersonal communication skills.