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DNA-encoded chemical library (DEL) postdoc
University of Utah in the Salt Lake City, Utah
 
 
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Date Posted 08/27/2020
Category
Postdoctoral-Chemistry
Employment Type Full-time
Application Deadline Open until filled
 
 
 
 
 

A postdoctoral scientist position is available in the Franzini group at the University of Utah. The scientist will participate in all aspects of DNA-encoded library (DEL) research. DELs are widely used in pharmaceutical research, and scientists trained in this area are in high demand. The Franzini group provides an ideal training environment to learn this technology. The appointment is anticipated to start Fall 2020. The work place will be located in the new Skaggs Pharmacy Research Building with access to state-of-the-art scientific facilities. The position is anticipated to last from one to three years.

An ideal candidate is highly motivated to advance his/her career by developing ambitious research projects. A minimal requirement is a Ph.D. granted within the last 0-3 years in Bioorganic Chemistry, Medicinal Chemistry, Organic Chemistry, Chemical Biology or a related discipline. The candidate should have excellent theoretical and practical knowledge of standard techniques in Chemistry and Biology. The candidate is expected to be an expert in at least some of the following areas: organic synthesis, bioconjugation, medicinal chemistry, and chemical biology. Meticulous working practices are critical for success with DELs. It is expected that the candidate is enthusiastic about learning new techniques and concepts. DEL research requires a flexible work schedule. Good interpersonal and communication skills (oral and written) are anticipated. A high degree of self-motivation and independence is required.

Responsibilities

The candidate will be responsible for:

  • Designing DELs
  • Synthesizing DELs
  • Performing DEL screens
  • Analyzing DEL screening data
  • Synthesizing hit compounds
  • Developing hits into leads by integrating DEL screening data with machine learning and structure-based drug discovery methods

A successful candidate should contribute to a positive work environment, which includes safe laboratory practices, and high scientific ethical standards.

Minimum Qualifications Preferences

Expertise with PCR, bioassays, and computational drug discovery are beneficial.

A candidate should be able to start within the next 3-4 months and therefore strong preference will be given to candidates that are currently present in the USA or are unlikely to fall under travel restrictions.

Type Benefited Staff Special Instructions Summary

Required documents: CV, cover letter explaining the motivation to apply for this position

Information about the research group can be found online:

https://franzini-research-group.squarespace.com/

Contact information: franzinilab@gmail.com

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