The Research Investigator (RI) will become part of a team focused on the role of voltage-gated ion channels in the neurobiology of learning and memory and neurodegenerative disease. The research program involves conducting studies in rodents to determine the neurobiological mechanisms which underlie the formation of short- and long-term memories in healthy subjects, as well as elucidating specific disruptions in these processes that contribute to impairments in learning and memory due to age or disease progression. To this end, the RI will be responsible for designing experiments and protocols, collecting and analyzing data, writing and publishing manuscripts in scientific journals, and presenting their work at local and national meetings. Further, RI will also be responsible for overseeing the training and work of junior lab members.
Must have a PhD in Neuroscience with at least seven years of postgraduate training. A strong publication record is required. Applicant must have extensive expertise using rodent animal models in the design and implementation of behavioral assays, electrophysiology, and molecular biological techniques. Specifically, experience with behavioral assays should include open field, light/dark box, novel object recognition, fear conditioning, radial arm maze, and Morris water maze. Experience with electrophysiology should include acute hippocampal slice preparation, whole-cell current- and voltage-clamp techniques, field recording, and optogenetic stimulation. Experience with molecular techniques should include PCR, Western blotting, ELISAs, tissue clearing methods, and immunohistochemistry.
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